Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | DKK1 | O94907 | 2/20 | 0.35 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515288 | 0.96 | CARM1 (0.39) | CARM1CTSSCTSKKMORAD52 | |
| SCHEMBL8536754 | 0.89 | DKK1 (0.40) | CTSSCTSKKMODKK1SORD | |
| SCHEMBL8515329 | 0.89 | ACHE (0.41) | CTSSCTSKKMODKK1SORD | |
| SCHEMBL8510840 | 0.83 | KMO (0.43) | KMODKK1SORD | |
| SCHEMBL8515556 | 0.83 | MEN1 (0.40) | CTSSCTSKKMODKK1SORD | |
| SCHEMBL8515286 | 0.83 | USP2 (0.35) | CTSSCTSKKMODKK1SORD | |
| SCHEMBL8511790 | 0.82 | ROCK2 (0.41) | KMODKK1 | |
| Hydrochloric Acid SCHEMBL8512525 | 0.81 | ROCK2 (0.41) | KMODKK1 | |
| SCHEMBL8514539 | 0.81 | KMO (0.45) | CTSSCTSKKMODKK1SORD | |
| SCHEMBL8510671 | 0.81 | DKK1 (0.44) | KMODKK1SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |