Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614490 | 0.92 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL9858293 | 0.81 | FFAR1 (0.47) | PPARGS1PR1PTGESALOX5FFAR1 | |
| SCHEMBL10420392 | 0.79 | TRPA1 (0.48) | S1PR1S1PR3ALOX5 | |
| SCHEMBL9613974 | 0.79 | TRPA1 (0.48) | S1PR1S1PR3ALOX5 | |
| SCHEMBL9613898 | 0.78 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9614190 | 0.77 | MMP3 (0.52) | PDE4APDE4BPDE4CPDE4DALOX5 | |
| SCHEMBL9614317 | 0.77 | MMP3 (0.52) | PDE4APDE4BPDE4CPDE4DALOX5 | |
| SCHEMBL9613976 | 0.76 | MMP2 (0.51) | PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL9614242 | 0.75 | TDP1 (0.43) | S1PR1S1PR3 | |
| SCHEMBL9614321 | 0.74 | CA2 (0.41) | PPARGPPARAPTGESALOX5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |