Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112845 | 0.83 | SDHB (0.40) | SDHBPAX8CA1CA2CA9 | |
| SCHEMBL8667528 | 0.75 | MAPT (0.56) | SDHBPGRALDH1A1GAALMNA | |
| SCHEMBL11236152 | 0.75 | LMNA (0.46) | SDHBPGRPTGS2BPTFALDH1A1 | |
| SCHEMBL1006428 | 0.75 | PAX8 (0.63) | PAX8CA1CA2CA9ALDH1A1 | |
| SCHEMBL6972835 | 0.73 | SDHB (0.40) | SDHBPGRPTGS2ALDH1A1LMNA | |
| SCHEMBL9120149 | 0.73 | MAPK8 (0.44) | PAX8CA1CA2CA9PGR | |
| SCHEMBL24262518 | 0.73 | KMT2A (0.61) | PAX8CA1CA2CA9ALDH1A1 | |
| SCHEMBL28281419 | 0.70 | PGR (0.44) | SDHBCA1CA2CA9PGR | |
| SCHEMBL14264137 | 0.70 | HTT (0.53) | PAX8ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL5198118 | 0.70 | KMT2A (0.64) | PAX8CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321784-B1 | FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0255890-B1 | PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |
| US-4841030-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0151792-B1 | REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0158882-B1 | TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4695632-A | ANIONIC DYE AFFINITY | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0097289-B1 | AZO DYESTUFFS | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0047863-A2 | Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| US-4280956-A | CONTAINING SULFONAMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |
| US-4126609-A | AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-21 | — | — | US | disclosed |
| US-4122079-A | Reactive azo dyestuffs from diazotized sulfo-amino naphthalenes and diaminosulfobenzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4089895-A | COUPLER FOR AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4049704-A | AZO REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-3989692-A | PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3988310-A | FIBER-REACTIVE DYES; CELLULOSE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3957751-A | WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |