SCHEMBL8667528

SCHEMBL8667528

Cc1cc(Oc2ccccc2)nc(S(C)(=O)=O)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
MAPK1 P28482 2/20 0.56
CYP2C19 P33261 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
HPGD P15428 2/20 0.56
ATM Q13315 1/20 0.56
HTT P42858 1/20 0.55
ALDH1A1 P00352 5/20 0.51
GAA P10253 1/20 0.51
TSHR P16473 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 5/20 0.46
SDHB P21912 1/20 0.45
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236152 0.84 LMNA (0.46) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL8665887 0.81 ALDH1A1 (0.62) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL8558105 0.78 ALDH1A1 (0.48) MAPTMEN1KMT2AMAPK1L3MBTL1
SCHEMBL17623918 0.76 MAPT (0.67) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL6561352 0.76 SMN1; SMN2 (0.78) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL6972835 0.76 SDHB (0.40) MAPTCYP1A2CYP2C9CYP2C19HTT
SCHEMBL9625959 0.75 SDHB (0.47) MEN1KMT2AMAPK1HPGDHTT
SCHEMBL28281419 0.74 PGR (0.44) MAPTCYP1A2CYP2C9CYP2C19HPGD
SCHEMBL23010902 0.73 MAPT (0.63) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL4528068 0.73 NPC1 (0.67) MAPTMEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
EP-0694538-A2 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-31 EP disclosed