SCHEMBL11236152

SCHEMBL11236152

CS(=O)(=O)c1cc(Oc2ccccc2)nc(S(C)(=O)=O)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SDHB P21912 2/20 0.45
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPK1 P28482 4/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 3/20 0.42
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PGR P06401 1/20 0.41
HTT P42858 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPSR1 Q6W5P4 3/20 0.40
NUDT1 P36639 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667528 0.84 MAPT (0.56) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL19402577 0.83 PGR (0.46) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL5360302 0.76 LMNA (0.78) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL6972835 0.76 SDHB (0.40) LMNASMN1; SMN2SDHBCYP1A2CYP2C9
SCHEMBL9625959 0.75 SDHB (0.47) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL28281419 0.74 PGR (0.44) LMNASMN1; SMN2SDHBCYP1A2CYP2C9
SCHEMBL9626200 0.73 LMNA (0.52) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL24156096 0.72 PGR (0.41) LMNASMN1; SMN2SDHBHPGDMAPT
SCHEMBL16608656 0.71 BPTF (0.41) LMNASMN1; SMN2SDHBMEN1KMT2A
SCHEMBL31287948 0.71 ALDH1A1 (0.57) LMNASMN1; SMN2SDHBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4354968-A Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component BAYER AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
US-4118382-A DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4065446-A Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US disclosed