Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630741 | 0.95 | PNMT (0.30) | PNMTCA1CA2CA7CA13 | |
| Potassium Ion SCHEMBL9631915 | 0.75 | PNMT (0.33) | PNMT | |
| SCHEMBL1024523 | 0.72 | CA1 (0.33) | CA1CA2CA7CA13 | |
| SCHEMBL1658730 | 0.70 | CA2 (0.45) | CA1CA2CA7CA13 | |
| SCHEMBL3573472 | 0.70 | EPHX1 (0.45) | CA1CA2CA7CA13 | |
| SCHEMBL2835677 | 0.70 | POLB (0.34) | CA1CA2CA7CA13 | |
| SCHEMBL31607593 | 0.70 | CA1 (0.32) | CA1CA2CA7CA13 | |
| SCHEMBL3371130 | 0.70 | CA1 (0.32) | CA1CA2CA7CA13 | |
| SCHEMBL9631930 | 0.70 | PNMT (0.33) | PNMT | |
| SCHEMBL15226205 | 0.68 | CETP (0.38) | CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283774-B1 | FLUORINATED ALKYLAMIDOSULFONATES, PREPARATION, USE AS FLAME-RETARDER AND POLYCARBONATE MOULDING MASSES CONTAINING THEM | BAYER AG (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0283774-A2 | Fluorinated alkylamidosulfonates, preparation, use as flame-retarder and polycarbonate moulding masses containing them | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |