Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417270 | 0.86 | MAPT (0.41) | MAPTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL11423221 | 0.84 | MAPT (0.40) | MAPTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL11418807 | 0.83 | MAPT (0.41) | MAPTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL11491083 | 0.82 | HTR1A (0.37) | MAPTKMT2AALDH1A1GAACYP1A2 | |
| SCHEMBL11418469 | 0.80 | ALDH1A1 (0.40) | MAPTKMT2ANPSR1MEN1ALDH1A1 | |
| SCHEMBL8942349 | 0.79 | CRHBP (0.47) | MAPTKMT2ANPSR1L3MBTL1CRHBP | |
| SCHEMBL11784247 | 0.79 | AMPD2 (0.50) | MAPTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL11419315 | 0.79 | CRHBP (0.34) | MAPTKMT2AL3MBTL1CRHBPCRHR2 | |
| SCHEMBL11780709 | 0.79 | MAPT (0.47) | MAPTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL596045 | 0.76 | DRD2 (0.46) | MAPTKMT2ANPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273868-B1 | N-SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIOXIDANTS FOR LUBRICANTS | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |
| EP-0273868-A2 | N-substituted tetrahydroquinolines as antioxidants for lubricants | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |