Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29250917 | 0.78 | HSP90AA1 (0.41) | LOXL2ALDH1A1 | |
| SCHEMBL5555345 | 0.77 | LOXL2 (0.39) | LOXL2 | |
| SCHEMBL7274937 | 0.74 | NOS2 (0.54) | KCNH2NOS2ALDH1A1TSHRNOS3 | |
| SCHEMBL2015524 | 0.74 | GRIN2D (0.44) | KCNH2ALDH1A1TSHRASIC3 | |
| SCHEMBL521804 | 0.74 | NOS2 (0.48) | NOS2NOS3 | |
| SCHEMBL2014831 | 0.74 | SMN1; SMN2 (0.39) | KCNH2ALDH1A1TSHRASIC3TP53 | |
| SCHEMBL522843 | 0.69 | ALDH1A1 (0.46) | LOXL2NOS2ALDH1A1CYP3A4NOS3 | |
| SCHEMBL13921937 | 0.69 | F11 (0.41) | LOXL2ALDH1A1 | |
| SCHEMBL20313918 | 0.69 | NOS2 (0.59) | KCNH2NOS2ALDH1A1TSHRNOS3 | |
| SCHEMBL522980 | 0.69 | TERT (0.37) | LOXL2NOS2ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094759-A | Method of water treatment using 2,6-substituted aminopyridines and polymer derived therefrom | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1992-03-10 | — | — | US | disclosed |
| US-5026802-A | Polymers derived from 2,6-substituted-4-amino-pyridines | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1991-06-25 | — | — | US | disclosed |