Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.54 |
| ▸ | HTR7 | P34969 | 6/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646137 | 0.83 | HTR1A (0.60) | HTR1AHTR7 | |
| SCHEMBL9646027 | 0.76 | HTR1A (0.55) | HTR1AHTR7ADORA2A | |
| SCHEMBL9646894 | 0.76 | HTR1A (0.70) | HTR1AHTR7 | |
| SCHEMBL8918838 | 0.76 | DRD4 (0.51) | HTR1AHTR7 | |
| SCHEMBL8918424 | 0.75 | HTR1A (0.51) | HTR1AHTR7 | |
| SCHEMBL7316292 | 0.74 | NPC1 (0.63) | — | |
| SCHEMBL9645787 | 0.74 | HTR1A (0.50) | HTR1AHTR7ADORA2A | |
| SCHEMBL9215528 | 0.74 | HTR7 (0.59) | HTR1AHTR7 | |
| SCHEMBL8918497 | 0.73 | DRD4 (0.53) | HTR1AHTR7 | |
| SCHEMBL9646338 | 0.73 | DRD2 (0.52) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |