Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651112 | 0.75 | GAA (0.40) | HCAR3GAAMAPTCCR2TSHR | |
| SCHEMBL7993476 | 0.70 | CCR2 (0.64) | GPR35MAPTCCR2TSHRALDH1A1 | |
| SCHEMBL9651130 | 0.70 | MAPT (0.42) | HCAR3GAAMAPTTSHRALDH1A1 | |
| SCHEMBL9651421 | 0.69 | HCAR3 (0.39) | HCAR3GAAMAPTCCR2ALDH1A1 | |
| SCHEMBL1415761 | 0.66 | CCR2 (0.63) | GPR35MAPTCCR2 | |
| SCHEMBL6180268 | 0.65 | HCAR3 (0.64) | HCAR3TSHRCASP6 | |
| SCHEMBL8330002 | 0.64 | GPR35 (0.53) | GPR35CCR2TSHRALDH1A1 | |
| SCHEMBL9651121 | 0.64 | PKM (0.37) | HCAR3GAAMAPTTSHRALDH1A1 | |
| SCHEMBL17399916 | 0.64 | CASP6 (0.60) | HCAR3TSHRCASP6 | |
| SCHEMBL10487614 | 0.63 | PTPN1 (0.46) | HCAR3GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517225-A1 | Aminopyrrolidine platinum compounds, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1992-12-09 | — | — | EP | disclosed |