SCHEMBL9660940

SCHEMBL9660940

CCCCCCCC(CCCCC)S(=O)(=O)[O-].[Na+]

nearest known ligand 0.47

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 7/20 0.45
CA1 known ✓ P00915 8/20 0.42
FDPS known ✓ P14324 3/20 0.39
CA12 known ✓ O43570 2/20 0.39
CA4 known ✓ P22748 2/20 0.39
RECQL P46063 2/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
EPHX2 P34913 1/20 0.47
BLM P54132 1/20 0.47
NR1I2 O75469 1/20 0.46
TP53 P04637 1/20 0.42
GPR84 Q9NQS5 4/20 0.41
CA9 Q16790 6/20 0.39
CA3 P07451 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28620971 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL28635347 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL28621346 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL9756753 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL8688848 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL28620924 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL28625565 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL17336061 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL17219439 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1
SCHEMBL28621299 1.00 RECQL (0.47) RECQLGLAHPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5109061-A Surfactants containing a polyurethane or polyurea polymer TEXACO CHEMICAL COMPANY (US) 1992-04-28 US disclosed
US-4735746-A WATER SOLUBLE POLYMER AND SURFACTANT TEXACO INC. (US) 1988-04-05 US disclosed
EP-0110440-A2 Inhibition of the staining of porcelain surfaces by manganese THE PROCTER & GAMBLE COMPANY (US) 1984-06-13 EP disclosed
US-4452713-A SODIUM OR POTASSIUM POLYPHOSPHATE AS OXIDATION INHIBITOR THE PROCTER & GAMBLE COMPANY (US) 1984-06-05 US disclosed
US-4428872-A ETHYLENE-MALEIC ANHYDRIDE COPOLYMER AS SEQUESTERING AGENT THE PROCTER & GAMBLE COMPANY (US) 1984-01-31 US disclosed
US-4420412-A USING AMMONIUM BROMIDE THE PROCTER & GAMBLE COMPANY (US) 1983-12-13 US disclosed
EP-0018344-B1 METHOD AND COMPOSITION TO INHIBIT STAINING OF PORCELAIN SURFACES BY MANGANESE, AND TOILET TANK DISPENSER USING THIS COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1983-06-22 EP disclosed
US-4384869-A Activation of hypochlorite bleaching of dyes THE PROCTER & GAMBLE COMPANY (US) 1983-05-24 US disclosed
EP-0018679-B1 SURFACTANT CAKE COMPOSITIONS CONTAINING SOLUBILITY REDUCING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1983-03-16 EP disclosed
US-4374572-A Method and composition to inhibit staining of porcelain surfaces by manganese THE PROCTER & GAMBLE COMPANY (US) 1983-02-22 US disclosed
US-4248827-A DISPENSING A HYPOCHLORITE AND AN OXIDIZABLE DYE THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4246129-A TOILET TANK DISPENSERS THE PROCTER & GAMBLE COMPANY (US) 1981-01-20 US disclosed
US-4235732-A ALKALINE AQUEOUS HYPOCHLORITE COMPOSITION CONTAINING A PARAFFIN SULFONATE SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1980-11-25 US disclosed
EP-0018679-A1 Surfactant cake compositions containing solubility reducing agents THE PROCTER & GAMBLE COMPANY (US) 1980-11-12 EP disclosed
EP-0018344-A1 Method and composition to inhibit staining of porcelain surfaces by manganese, and toilet tank dispenser using this composition THE PROCTER & GAMBLE COMPANY (US) 1980-10-29 EP disclosed
US-4216027-A Method and apparatus for cleansing and disinfecting a flushing toilet THE PROCTER & GAMBLE COMPANY (US) 1980-08-05 US disclosed
EP-0013043-A1 Method of treating a flush toilet with separate hypochlorite/dye dispensers and article for placement in the flush tank THE PROCTER & GAMBLE COMPANY (US) 1980-07-09 EP disclosed
US-4200606-A HYPOCHLORITE AND FD AND C BLUE NO. 1 AND GREEN NO. 3 THE PROCTER & GAMBLE COMPANY (US) 1980-04-29 US disclosed
EP-0004991-A1 Method and apparatus for cleansing and disinfecting a flushing toilet THE PROCTER & GAMBLE COMPANY (US) 1979-10-31 EP disclosed
EP-0003625-A1 Liquid cleaning compositions containing hypochlorite and paraffin sulfonates THE PROCTER & GAMBLE COMPANY (US) 1979-08-22 EP disclosed