Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677235 | 0.88 | HTR6 (0.44) | HTR6CNR1RIPK1MAPTMEN1 | |
| SCHEMBL9677343 | 0.80 | HTR6 (0.46) | HTR6CNR1RIPK1MAPTMEN1 | |
| SCHEMBL9679257 | 0.78 | RIPK1 (0.36) | HTR6RIPK1MAPT | |
| Glipalamide SCHEMBL1816058 | 0.74 | LMNA (0.46) | MAPTALDH1A1KMT2APOLB | |
| SCHEMBL9679153 | 0.73 | HTR6 (0.42) | RORCHTR6CNR1HSD11B1 | |
| SCHEMBL9678547 | 0.72 | RIPK1 (0.39) | HTR6RIPK1POLB | |
| SCHEMBL9678285 | 0.72 | MEN1 (0.34) | RORCHTR6CNR1MEN1KMT2A | |
| SCHEMBL9678539 | 0.72 | HTR6 (0.49) | HTR6RIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9678674 | 0.72 | MAPT (0.40) | RIPK1MAPTPOLB | |
| SCHEMBL9676475 | 0.71 | POLB (0.59) | HTR6RIPK1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |