SCHEMBL9679869

SCHEMBL9679869

Oc1nc(S)nc2nccnc12

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321932 0.82 ADORA2A (0.40) ADORA2A
SCHEMBL30361253 0.82 ADORA2A (0.40) ADORA2A
SCHEMBL12261736 0.74 ADORA2A (0.63) ADORA2A
Pterine SCHEMBL4364328 0.74 ADORA2A (0.63) ADORA2A
SCHEMBL687166 0.74 ADORA2A (0.38) ADORA2A
SCHEMBL30570890 0.74 ADORA2A (0.38) ADORA2A
SCHEMBL13596901 0.72 ALDH1A1 (0.35)
SCHEMBL686727 0.69 PDE4A (0.38) ADORA2A
SCHEMBL7977529 0.69 KDM4E (0.37)
SCHEMBL8945215 0.69 MMP2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0483426-A1 Thiol heterocyclic deodorant composition and method of deodorization THE PROCTER & GAMBLE COMPANY (US) 1992-05-06 EP claimed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
US-20250241872-A1 AFFINITY MEDICANT CONJUGATE Illudent, Inc. (US) 2025-07-31 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
US-12269793-B2 Affinity illudofulvene conjugates AF CHEMICALS, LLC (US) 2025-04-08 US disclosed
EP-4257186-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2024-12-04 EP disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
EP-4257186-A2 AFFINITY MEDICANT CONJUGATES AF Chemicals LLC (US) 2023-10-11 EP disclosed
EP-3129357-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2023-08-23 EP disclosed
US-20230212113-A1 AFFINITY ILLUDOFULVENE CONJUGATES AF Chemicals, LLC, (US) 2023-07-06 US disclosed
US-20210077425-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2021-03-18 US disclosed
US-10806708-B2 Affinity medicant conjugate AF CHEMICALS LLC (US) 2020-10-20 US disclosed
US-10285955-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2019-05-14 US disclosed
US-20180263927-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2018-09-20 US disclosed
US-9980926-B1 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2018-05-29 US disclosed
EP-3129357-A2 AFFINITY MEDICANT CONJUGATES AF Chemicals LLC (US) 2017-02-15 EP disclosed
US-9381178-B2 Affinity medicant conjugate AF CHEMICALS LLC (US) 2016-07-05 US disclosed
US-20160015658-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC 2016-01-21 US disclosed
US-20150290152-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC 2015-10-15 US disclosed
EP-0483426-A1 Thiol heterocyclic deodorant composition and method of deodorization THE PROCTER & GAMBLE COMPANY (US) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 ADORA2A 1973/4885
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-20230212113-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 ADORA2A 1973/4885
US-20160015658-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-20150290152-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-10285955-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-12269793-B2 Affinity illudofulvene conjugates OGFR, TNFSF11, FCER2 ADORA2A 1973/4885
US-10806708-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A ADORA2A 1740/4885
US-20180263927-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ADORA2A 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.