Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681433 | 0.89 | CFTR (0.42) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL9680331 | 0.87 | RARA (0.40) | RARARARBRARGALDH1A1RAB9A | |
| SCHEMBL9682059 | 0.81 | MAPT (0.45) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL9682898 | 0.81 | RARA (0.32) | RARARARBRARGKDM4EMAPT | |
| SCHEMBL12365911 | 0.79 | RARA (0.43) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL9682129 | 0.78 | ALDH1A1 (0.36) | ALDH1A1RAB9AMAPTSMN1; SMN2CASP3 | |
| SCHEMBL9680361 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1OPRD1MEN1KMT2A | |
| SCHEMBL2263334 | 0.78 | RARA (0.43) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL12365916 | 0.78 | NPC1 (0.44) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL9680947 | 0.77 | PDPK1 (0.43) | RARARARBRARGKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |