Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682106 | 0.87 | ALDH1A1 (0.42) | NPSR1KDM4EMAPT | |
| SCHEMBL9680894 | 0.85 | RARA (0.33) | RARARARBRARGNPSR1MAPT | |
| SCHEMBL9680361 | 0.84 | KDM4E (0.36) | KDM4E | |
| SCHEMBL9682129 | 0.84 | ALDH1A1 (0.36) | NPSR1MAPT | |
| SCHEMBL9680897 | 0.75 | ALDH1A1 (0.43) | NPSR1KDM4EMAPT | |
| SCHEMBL9680903 | 0.74 | SMN1; SMN2 (0.41) | NPSR1KDM4EMAPT | |
| SCHEMBL9680365 | 0.74 | PBRM1 (0.35) | RARARARBRARGKDM4E | |
| SCHEMBL9681507 | 0.72 | CASP1 (0.42) | KDM4EMAPT | |
| SCHEMBL9681489 | 0.72 | ALDH1A1 (0.41) | NPSR1KDM4EMAPT | |
| SCHEMBL9680406 | 0.71 | POLB (0.45) | RARARARBRARGKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |