Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682898 | 0.85 | RARA (0.32) | RARARARBRARGNPSR1MAPT | |
| SCHEMBL9682156 | 0.82 | ALDH1A1 (0.38) | PTPRCMEN1KMT2ARAB9AMALT1 | |
| SCHEMBL9682813 | 0.82 | PDE4A (0.37) | MALT1 | |
| SCHEMBL9682106 | 0.81 | ALDH1A1 (0.42) | NPSR1MEN1KMT2AMAPTHTT | |
| SCHEMBL9680331 | 0.80 | RARA (0.40) | RARARARBRARGNPSR1MEN1 | |
| SCHEMBL9680365 | 0.77 | PBRM1 (0.35) | RARARARBRARGPBRM1PTPRC | |
| SCHEMBL24727857 | 0.71 | RARA (0.54) | RARARARBRARGPBRM1NPSR1 | |
| SCHEMBL9527732 | 0.69 | ABCC9 (0.41) | RARARARBRARG | |
| SCHEMBL8085076 | 0.69 | NPSR1 (0.34) | PBRM1NPSR1PTPRCMEN1KMT2A | |
| SCHEMBL9524965 | 0.68 | ADRA1A (0.39) | RARARARBRARGCTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |