Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682829 | 0.92 | BCHE (0.41) | HTR1ABCHELTA4HMAPK14NPC1 | |
| SCHEMBL9682833 | 0.92 | BCHE (0.41) | HTR1ABCHELTA4HMAPK14NPC1 | |
| SCHEMBL4903979 | 0.79 | MAPT (0.46) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9703060 | 0.75 | ALDH1A1 (0.34) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9683450 | 0.73 | LMNA (0.49) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9681836 | 0.71 | LMNA (0.47) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL4157654 | 0.71 | ABCB1 (0.49) | HTR1AADRA1DADRA1AADRA1BBCHE | |
| SCHEMBL4688019 | 0.70 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9237762 | 0.70 | BCHE (0.49) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL7720531 | 0.70 | LTA4H (0.49) | HTR1ALMNALTA4HMAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498380-A1 | Complexing agents | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-08-12 | — | — | EP | disclosed |