Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688019 | 0.90 | HTR1A (0.43) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9237762 | 0.90 | BCHE (0.49) | L3MBTL1LMNAHTR1AADRA1DADRA1A | |
| SCHEMBL4157654 | 0.89 | ABCB1 (0.49) | NPC1RAB9ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL15088139 | 0.85 | HTR1A (0.38) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19463829 | 0.83 | THRA (0.43) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1178876 | 0.81 | LTA4H (0.58) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9682833 | 0.81 | BCHE (0.41) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9682829 | 0.81 | BCHE (0.41) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9682277 | 0.79 | HTR1A (0.42) | L3MBTL1NPC1RAB9ASMN1; SMN2CCNB2 | |
| SCHEMBL7720531 | 0.77 | LTA4H (0.49) | MAPTL3MBTL1SMN1; SMN2LTA4HMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | BTG INTERNATIONAL LIMITED | 2008-08-21 | — | — | US | disclosed |
| WO-2006103463-A1 | IRON MODULATORS | BTG INTERNATIONAL LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |
| WO-1992013841-A1 | COMPLEXING AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498380-A1 | Complexing agents | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | SLC40A1, HAMP, FTH1 | MAPT 109/4885L3MBTL1 793/4885NPC1 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.