Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683129 | 0.86 | MAPT (0.47) | TP53TSHRALDH1A1 | |
| SCHEMBL16489601 | 0.85 | ALDH1A1 (0.46) | TSHRALDH1A1GAAFFAR1SSTR3 | |
| SCHEMBL9683458 | 0.84 | SSTR3 (0.51) | TSHRALDH1A1GAAFFAR1SSTR3 | |
| SCHEMBL10507600 | 0.82 | SSTR3 (0.51) | ALDH1A1GAAFFAR1SSTR3 | |
| SCHEMBL11569274 | 0.81 | ALDH1A1 (0.49) | TP53ALDH1A1GAA | |
| SCHEMBL9682901 | 0.81 | MAPT (0.43) | TP53TSHRALDH1A1GAA | |
| SCHEMBL9681376 | 0.80 | MAPT (0.46) | MRGPRX4FFAR1 | |
| SCHEMBL11274390 | 0.80 | PKM (0.52) | ALDH1A1MRGPRX4GAA | |
| SCHEMBL9683167 | 0.77 | HTT (0.51) | GAA | |
| SCHEMBL9683493 | 0.77 | MEN1 (0.59) | TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |