Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683479 | 0.90 | AKR1B1 (0.43) | TRPM5MEN1KMT2AADRA2BCYP1A2 | |
| SCHEMBL6744214 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP3A4CA1CA2 | |
| SCHEMBL11569274 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9683129 | 0.76 | MAPT (0.47) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15076829 | 0.75 | CXCR3 (0.43) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9683485 | 0.75 | MAPT (0.60) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9681422 | 0.74 | HDAC1 (0.40) | ADRA2BALDH1A1AKR1B1HDAC1 | |
| SCHEMBL11274390 | 0.73 | PKM (0.52) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3787955 | 0.72 | ALDH1A1 (0.54) | KMT2AALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL13881914 | 0.72 | SLC6A4 (0.58) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |