Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068659 | 0.82 | KIF11 (0.64) | KIF11HTR1AHTR2CCDK2AKT1 | |
| SCHEMBL24575928 | 0.82 | KIF11 (0.64) | KIF11HTR1AHTR2CCDK2AKT1 | |
| SCHEMBL9205683 | 0.81 | HTR1A (0.53) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL9686038 | 0.80 | ALDH1A1 (0.51) | HTR1AHTR2CPDE3BPDE3ADAO | |
| SCHEMBL9685648 | 0.80 | CMA1 (0.56) | HTR1AHTR2CPDE3BPDE3ADAO | |
| SCHEMBL27353257 | 0.79 | AKT1 (0.59) | KIF11HTR1AHTR2CCDK2AKT1 | |
| SCHEMBL7760532 | 0.79 | HTR1A (0.50) | KIF11HTR1AHTR2CCDK2AKT1 | |
| SCHEMBL9685728 | 0.77 | PDE3B (0.69) | HTR1AHTR2CPDE3BPDE3AIDH1 | |
| SCHEMBL9686113 | 0.76 | PGR (0.50) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL9484037 | 0.75 | KIF11 (0.50) | KIF11HTR1AHTR2CCDK2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |