Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727639 | 0.98 | BBOX1 (0.43) | BBOX1KDM4EMAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL21801821 | 0.89 | BBOX1 (0.36) | BBOX1KDM4EATMACHETHRB | |
| Hydrochloric Acid SCHEMBL6117375 | 0.86 | BBOX1 (0.42) | BBOX1KDM4EMAPK1HIF1AKMT2A | |
| SCHEMBL969702 | 0.85 | BBOX1 (0.37) | BBOX1 | |
| Hydrochloric Acid SCHEMBL1603052 | 0.85 | KDM4E (0.33) | KDM4EMAPK1HIF1AKMT2AATM | |
| SCHEMBL3764634 | 0.84 | BBOX1 (0.43) | BBOX1KDM4EMAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL475592 | 0.84 | CHRM2 (0.35) | KDM4EMAPK1HIF1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27571208 | 0.84 | ACHE (0.42) | BBOX1KDM4EMAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL61004 | 0.84 | ACHE (0.42) | BBOX1KDM4EMAPK1HIF1AKMT2A | |
| Fluoride Ion SCHEMBL8583069 | 0.83 | BBOX1 (0.42) | BBOX1KDM4EMAPK1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956397-A1 | SEPARATING FIBERS BY MEANS OF POLYION COMPLEXES | Ionys AG (DE) | 2022-02-23 | — | — | EP | claimed |
| WO-2020212359-A1 | SEPARATING FIBERS BY MEANS OF POLYION COMPLEXES | IONYS AG (DE) | 2020-10-22 | — | — | WO | claimed |
| US-9469713-B2 | Ampholytic ter-polymers for use in personal care compositions | BASF SE (DE) | 2016-10-18 | — | — | US | claimed |
| WO-2016022161-A1 | KERATIN CONDITIONING POLYMERS FOR USE IN PERSONAL CARE COMPOSITONS | BASF SE (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2015054452-A1 | KERATIN CONDITIONING BIO-BASED POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2015-04-16 | — | — | WO | claimed |
| US-20140147399-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2014-05-29 | — | — | US | claimed |
| US-8663612-B2 | Ampholytic ter-polymers for use in personal care compositions | BASF SE (DE) | 2014-03-04 | — | — | US | claimed |
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2010-09-09 | — | — | US | claimed |
| WO-2025111428-A1 | METHOD FOR PRODUCTION OF VINYL CARBOXAMIDE CONTAINING POLYMERS IN PARTICULATE FORM | SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) | 2025-05-30 | — | — | WO | disclosed |
| WO-2025111424-A1 | PARTICULATE VINYLAMINE COMPOSITIONS AND METHOD OF MAKING | SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) | 2025-05-30 | — | — | WO | disclosed |
| WO-2025111425-A1 | A METHOD OF PRODUCING VINYLAMINE-CONTAINING POLYMERS | SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) | 2025-05-30 | — | — | WO | disclosed |
| US-20250163646-A1 | PARTICULATE VINYLAMINE COMPOSITIONS AND METHOD OF MAKING | SOLENIS TECHNOLOGIES, L.P. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250163194-A1 | METHOD OF PRODUCING VINYLAMINE-CONTAINING POLYMERS | SOLENIS TECHNOLOGIES, L.P. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250163647-A1 | METHOD FOR PRODUCTION OF VINYL CARBOXAMIDE CONTAINING POLYMERS IN PARTICULATE FORM | SOLENIS TECHNOLOGIES, L.P. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2010-09-09 | — | — | US | disclosed |
| EP-1911778-B1 | COPOLYMER AND DETERGENT COMPOSITIONS CONTAINING THE SAME | MITSUBISHI CHEM CORP (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20100105592-A1 | COPOLYMER AND DETERGENT COMPOSITIONS CONTAINING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-1911778-A1 | COPOLYMER AND DETERGENT COMPOSITIONS CONTAINING THE SAME | Mitsubishi Chemical Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20070167593-A1 | Water-soluble resin, hair cosmetic material containing the same, and silicone oil adsorption assistant | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1719785-A1 | WATER-SOLUBLE RESIN, COSMETIC HAIR PREPARATION CONTAINING THE SAME, AND SILICONE OIL ADSORPTION AID | Mitsubishi Chemical Corporation (JP) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147399-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | KRT18, CUTA, PRKDC | ACHE 1327/4885BBOX1 672/4885KDM4E 1257/4885 |
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | KRT18, CUTA, PRKDC | ACHE 1327/4885BBOX1 672/4885KDM4E 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.