Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1548103 | 0.87 | DNM1 (0.39) | KDM4ETGFBR1MAPK1HIF1AKMT2A | |
| SCHEMBL8428426 | 0.85 | DNM1 (0.40) | KDM4ETGFBR1MAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL968646 | 0.85 | BBOX1 (0.42) | KDM4EMAPK1HIF1AKMT2AATM | |
| Hydrochloric Acid SCHEMBL10425314 | 0.83 | CBLB (0.37) | KDM4ETGFBR1MAPK1HIF1AKMT2A | |
| SCHEMBL1727639 | 0.83 | BBOX1 (0.43) | KDM4ETGFBR1MAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL61004 | 0.82 | ACHE (0.42) | KDM4EMAPK1HIF1AKMT2AATM | |
| Hydrochloric Acid SCHEMBL27571208 | 0.82 | ACHE (0.42) | KDM4EMAPK1HIF1AKMT2AATM | |
| Hydrochloric Acid SCHEMBL1201070 | 0.81 | ACHE (0.41) | KDM4EMAPK1HIF1AKMT2AATM | |
| Acetic Acid SCHEMBL1325311 | 0.81 | DNM1 (0.37) | KDM4ETGFBR1KMT2AATML3MBTL1 | |
| SCHEMBL25422694 | 0.80 | ACHE (0.43) | KDM4ETGFBR1MAPK1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | JOHNSON & JOHNSON CONSUMER INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-8399590-B2 | Superhydrophilic amphiphilic copolymers and processes for making the same | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2013-03-19 | — | — | US | disclosed |
| US-8258250-B2 | Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110082290-A1 | SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2011-04-07 | — | — | US | disclosed |
| US-20110081310-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110081309-A1 | COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER | KENVUE BRANDS LLC | 2011-04-07 | — | — | US | disclosed |
| US-20110082105-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | KENVUE BRANDS LLC | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082105-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | PHOSPHO1, LIPA, ABHD16A | KDM4E 4663/4885PSMD14 3450/4885PLA2G1B 161/4885 |
| US-20110081310-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | ABHD16A, LIPA, ABHD12 | KDM4E 3479/4885PSMD14 2157/4885PLA2G1B 312/4885 |
| US-20110081309-A1 | COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER | ABHD16A, DSG1, CUTA | KDM4E 2986/4885PSMD14 468/4885PLA2G1B 651/4885 |
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | ABHD16A, DSG1, CUTA | KDM4E 2986/4885PSMD14 468/4885PLA2G1B 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.