Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749398 | 0.79 | GABRA1 (0.42) | HPGDHSD17B10MAPTADRA2AADRA2B | |
| SCHEMBL10485175 | 0.78 | MAPT (0.40) | HPGDMAPTALDH1A1 | |
| SCHEMBL23744209 | 0.77 | ADRA1D (0.50) | HPGDTSHRMAPK1HSD17B10GCGR | |
| SCHEMBL9687890 | 0.76 | CYP1A2 (0.39) | HPGDTSHRMAPK1HSD17B10GCGR | |
| SCHEMBL7764770 | 0.76 | HPGD (0.55) | HPGDTSHRMAPK1HSD17B10GCGR | |
| SCHEMBL10749903 | 0.74 | TGFBR1 (0.39) | HPGDATMSQORALDH1A1 | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.70 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.70 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL515196 | 0.70 | ADRB2 (0.59) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL6663936 | 0.68 | HTR7 (0.53) | HPGDTSHRMAPK1HSD17B10GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477901-A2 | Cyclohexylphenylpyrimidines, process for their preparation und their use in liquid crystal compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-01 | — | — | EP | disclosed |