Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687454 | 0.90 | MEN1 (0.39) | MEN1KMT2ATRPV1ALDH1A1MAPT | |
| SCHEMBL9687366 | 0.88 | PDE2A (0.41) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL9164713 | 0.84 | MMP13 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9687941 | 0.83 | EZH2 (0.40) | MEN1KMT2ASMN1; SMN2KDM4EHDAC1 | |
| SCHEMBL9688033 | 0.80 | HTT (0.49) | CYP1A2CYP3A4MEN1KMT2ACYP2C19 | |
| SCHEMBL9687391 | 0.77 | HPGD (0.39) | MEN1KMT2APOLBTSHRNPSR1 | |
| SCHEMBL9688037 | 0.75 | TSHR (0.49) | KMT2APOLBTSHRALDH1A1LMNA | |
| SCHEMBL9280239 | 0.72 | RXFP1 (0.45) | MEN1KMT2ATSHRTRPV1ALDH1A1 | |
| SCHEMBL9687701 | 0.72 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL9278822 | 0.70 | RAB9A (0.46) | MEN1KMT2APOLBTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |