Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026198 | 0.76 | LMNA (0.39) | NPC1RAB9ASMN1; SMN2GAAHPGD | |
| SCHEMBL9687941 | 0.75 | EZH2 (0.40) | NPC1SMN1; SMN2HPGD | |
| SCHEMBL9687454 | 0.74 | MEN1 (0.39) | ALDH1A1 | |
| SCHEMBL9687391 | 0.69 | HPGD (0.39) | NPC1SMN1; SMN2GAAHPGDTSHR | |
| SCHEMBL9160957 | 0.61 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHR | |
| SCHEMBL8252004 | 0.57 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15684258 | 0.56 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2HPGDTSHR | |
| SCHEMBL16535922 | 0.56 | LIPG (0.60) | LIPG | |
| SCHEMBL16535923 | 0.56 | LIPG (0.60) | LIPG | |
| SCHEMBL16543210 | 0.54 | LIPG (0.64) | LIPGNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |