Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688895 | 0.81 | KDM4E (0.43) | GPR139KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL9689963 | 0.77 | HDAC3 (0.43) | KDM4EHSD11B1MAPTALDH1A1HPGD | |
| SCHEMBL9690031 | 0.77 | TDP1 (0.40) | GPR139KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL9689940 | 0.77 | TDP1 (0.40) | GPR139KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9689439 | 0.76 | KDM4E (0.45) | GPR139KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL9688515 | 0.74 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1HPGDTDP1 | |
| SCHEMBL9689971 | 0.74 | ALDH1A1 (0.35) | GPR139KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL9688569 | 0.74 | KDM4E (0.43) | GPR139KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL9689482 | 0.72 | ALDH1A1 (0.34) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL9689433 | 0.71 | ALDH1A1 (0.49) | KDM4EHSD11B1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |