Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688526 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HSD17B10KDM4EHPGDECE1 | |
| SCHEMBL9690031 | 0.76 | TDP1 (0.40) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL9689940 | 0.76 | TDP1 (0.40) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL9689975 | 0.74 | GPR139 (0.37) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL9689971 | 0.73 | ALDH1A1 (0.35) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL9688895 | 0.72 | KDM4E (0.43) | ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9689482 | 0.71 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL9690657 | 0.68 | NPSR1 (0.38) | MAPTPOLB | |
| SCHEMBL9689963 | 0.65 | HDAC3 (0.43) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9690025 | 0.64 | PPARA (0.42) | ALDH1A1KDM4EALOX15SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |