SCHEMBL9700883

SCHEMBL9700883

CC(C)c1cc(N(C=O)c2ccccc2)cc(C(C)C)c1N

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700695 0.76 DHFR (0.38) GABRA1
SCHEMBL9700902 0.75 POLB (0.36)
SCHEMBL5516786 0.74 ALDH1A1 (0.42)
SCHEMBL43388 0.74 ALDH1A1 (0.42)
SCHEMBL1487730 0.72 TSPO (0.41)
SCHEMBL9699565 0.71 CYP3A4 (0.58)
SCHEMBL28084037 0.69 TDP1 (0.36)
SCHEMBL172583 0.67 CA12 (0.44)
SCHEMBL1491936 0.67 CA1 (0.43) GABRA1
SCHEMBL9216448 0.67 RAB9A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114975-A Insecticides and miticides CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed
US-5026730-A Anilinophenylthioureas, compositions containing them, and the use thereof in pest control CIBA-GEIGY CORPORATION (US) 1991-06-25 US disclosed