Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735080 | 0.86 | TSHR (0.42) | ALDH1A1TSHRMAPK1KDM4EMAPT | |
| SCHEMBL9733607 | 0.85 | DRD1 (0.35) | ALDH1A1TSHRMAPK1KDM4EMAPT | |
| SCHEMBL9734096 | 0.82 | ABCC9 (0.41) | LMNABACE1 | |
| SCHEMBL9733350 | 0.82 | HIF1A (0.41) | ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL9737119 | 0.81 | MAOA (0.40) | ALDH1A1POLBKDM4EMAPTL3MBTL1 | |
| SCHEMBL9732909 | 0.81 | OPRD1 (0.35) | ALDH1A1TSHRMAPK1KDM4EMAPT | |
| SCHEMBL9733550 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TSHRPOLBMAPTPARP1 | |
| SCHEMBL9589012 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRPOLBMAPK1PARP1 | |
| SCHEMBL9733240 | 0.78 | CYP11B2 (0.35) | ALDH1A1TSHRPOLBMAPTOPRM1 | |
| SCHEMBL9733605 | 0.78 | FAAH (0.37) | ALDH1A1TSHRPOLBPARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |