Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151601 | 0.86 | LMNA (0.57) | PTPN11KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10751518 | 0.77 | PTPN11 (0.56) | PTPN11KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3135517 | 0.76 | LMNA (0.74) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10438816 | 0.75 | HTR7 (0.53) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL385606 | 0.75 | LMNA (0.72) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| Lithium SCHEMBL385607 | 0.75 | LMNA (0.72) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5149366 | 0.74 | PTGER1 (0.62) | PTPN11KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8014661 | 0.73 | RXRA (0.61) | PTPN11KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9837607 | 0.73 | L3MBTL1 (0.52) | PTPN11ABL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL27301114 | 0.73 | ADRB2 (0.63) | KDM4ELMNASMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |