Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358517 | 0.90 | CYP2C9 (0.49) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL9703208 | 0.83 | HTR4 (0.61) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL7305753 | 0.76 | CNR1 (0.52) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL7358522 | 0.74 | HTR4 (0.60) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL9265705 | 0.72 | PLD2 (0.41) | — | |
| SCHEMBL7300888 | 0.72 | HTR4 (0.77) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| Hydrochloric Acid SCHEMBL7291228 | 0.71 | HTR4 (0.76) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL7302781 | 0.71 | HTR4 (0.45) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL7291933 | 0.70 | HTR4 (0.61) | HTR4CYP2C9NPSR1PMP22CYP1A2 | |
| SCHEMBL7294476 | 0.70 | CYP2C9 (0.52) | HTR4CYP2C9NPSR1PMP22CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014727-A1 | 3-PIPERIDINYLMETHYLCARBOXYLATE SUBSTITUTED INDOLES | GLAXO GROUP LIMITED (GB) | 1992-09-03 | — | — | WO | claimed |