SCHEMBL9706883

SCHEMBL9706883

[SiH3]C1(CCC(CCl)c2ccccc2)CCCCO1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27763048 0.86 GABBR2 (0.36) OPRM1
SCHEMBL7243099 0.81 RIPK1 (0.38) OPRM1
SCHEMBL2404032 0.75 ALDH1A1 (0.39) OPRM1
SCHEMBL4284401 0.74 OPRM1 (0.31) OPRM1
SCHEMBL15855926 0.73 OPRM1 (0.37) OPRM1
SCHEMBL477537 0.72 KDM1A (0.35) OPRM1
SCHEMBL11045956 0.72
SCHEMBL4533819 0.71 TAAR1 (0.37) OPRM1
SCHEMBL19875037 0.70 POLB (0.35) OPRM1
SCHEMBL338864 0.70 SIGMAR1 (0.37) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11525962-B2 Optical fiber alignment device with self-healing refractive index-matching gel of polysiloxane and method of making COMMSCOPE TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-20210356676-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2021-11-18 US disclosed
US-11054583-B2 Optical fiber alignment device with self-healing refractive index-matching gel COMMSCOPE TECHNOLOGIES LLC (US) 2021-07-06 US disclosed
US-20200116947-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2020-04-16 US disclosed
EP-3635461-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL Commscope Technologies LLC (US) 2020-04-15 EP disclosed
WO-2018226872-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2018-12-13 WO disclosed
US-5079300-A Curable Gel RAYCHEM CORPORATION (US) 1992-01-07 US disclosed
EP-0461185-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1991-12-18 EP disclosed
WO-1990010035-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1990-09-07 WO disclosed