Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 5/20 | 0.40 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707814 | 0.94 | ADORA3 (0.42) | HPGDUSP1 | |
| SCHEMBL9708010 | 0.93 | MAPT (0.41) | USP1 | |
| SCHEMBL9708391 | 0.92 | PDE1A (0.44) | HPGDUSP1 | |
| SCHEMBL9707977 | 0.92 | ALDH1A1 (0.44) | ATM | |
| SCHEMBL9707902 | 0.91 | HPGD (0.43) | HPGD | |
| SCHEMBL9708350 | 0.91 | ADORA3 (0.43) | — | |
| SCHEMBL9708054 | 0.90 | USP1 (0.42) | HPGDUSP1 | |
| SCHEMBL9708311 | 0.90 | ADORA1 (0.42) | — | |
| SCHEMBL9708133 | 0.90 | PDE5A (0.41) | HPGDUSP1 | |
| SCHEMBL9707502 | 0.90 | ADORA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |