Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865067 | 0.81 | LMNA (0.38) | MC4RKMT2AMEN1RXFP1HPGD | |
| SCHEMBL9709040 | 0.72 | RAB9A (0.52) | MC4RKMT2AMEN1HPGD | |
| SCHEMBL228875 | 0.68 | POLB (0.44) | HDAC8 | |
| SCHEMBL8790882 | 0.67 | MC4R (0.55) | MC4RHPGDLMNANPSR1HSD17B10 | |
| SCHEMBL7779326 | 0.60 | MEN1 (0.42) | KMT2AMEN1LMNANPSR1HSD17B10 | |
| SCHEMBL10408103 | 0.59 | KMT2A (0.49) | MC4RKMT2AMEN1RXFP1HPGD | |
| SCHEMBL7434053 | 0.59 | HPGD (0.46) | KMT2AHPGDSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6814764 | 0.58 | POLB (0.51) | — | |
| SCHEMBL9516562 | 0.58 | POLB (0.37) | KMT2AMEN1SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL11901003 | 0.57 | KMT2A (0.89) | KMT2AHPGDL3MBTL1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066549-A1 | INTERMEDIATE COMPOUNDS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-09-13 | — | — | WO | disclosed |