Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1578668 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL27901803 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL208379 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL67093 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3229957 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28547967 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL368324 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL19716175 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7804771 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3798286 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075782-A | Double-waveband optical response bimetallic MOFs modified titanium implant and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122037641-A | Corrosion-resistant protective varnish for automobile air inlet grille and preparation method thereof | 长春富维高新汽车饰件有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122013234-A | Anti-poisoning electrocatalytic ammoxidation catalyst based on bimetallic-polyoxometallate interface and preparation method thereof | 上海澳思净科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120132882-A | Nanowire nickel oxide-copper nitride loaded graphene composite material, preparation method thereof and application thereof in catalyzing ammonia borane hydrolysis hydrogen production | 惠州学院 | 2025-06-13 | — | — | CN | claimed |
| WO-2025122837-A1 | METHOD TO IMPROVE FIRE-RESISTANCE OF WOOD COMPOSITES, CELLULAR SOLIDS AND POROUS MATERIALS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2025-06-12 | — | — | WO | claimed |
| CN-120118329-A | Nitrogen-phosphorus co-doped metal organic framework flame retardant material and preparation method and application thereof | 中国地质大学（武汉） | 2025-06-10 | — | — | CN | claimed |
| CN-116514134-B | Preparation method of modified 13X molecular sieve with improved adsorption performance and selectivity | 宁夏大学 | 2025-06-03 | — | — | CN | claimed |
| CN-120059213-A | Asymmetric spiral chain Cu-MOF material and preparation method and application thereof | 湘潭大学 | 2025-05-30 | — | — | CN | claimed |
| CN-117003614-B | Preparation method of bio-based 1, 4-butanediol | 浙江博聚新材料有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119900049-A | Preparation and application of porous titanium carbide loaded copper molybdenum sulfide electrode material | 哈尔滨理工大学 | 2025-04-29 | — | — | CN | claimed |
| US-6209343-B1 | Portable apparatus for storing and/or transporting biological samples, tissues and/or organs | LIFE SCIENCE HOLDINGS, INC. | 2001-04-03 | — | — | US | claimed |
| WO-2000018225-A1 | PORTABLE APPARATUS FOR STORING AND/OR TRANSPORTING BIOLOGICAL SAMPLES, TISSUES AND/OR ORGANS | ORGAN RECOVERY SYSTEMS, INC. (US) | 2000-04-06 | — | — | WO | claimed |
| US-5788990-A | Water-repellent powder and manufacture of the same | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-08-04 | — | — | US | claimed |
| EP-0358530-B1 | Novel method for producing ceramic bodies | DOW CHEMICAL CO (US) | 1994-04-20 | — | — | EP | claimed |
| US-5145833-A | Superconductor, yttrium-barium-copper oxide, compression, isostatic pressing | THE DOW CHEMICAL COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| WO-1990002715-A1 | NOVEL METHOD FOR PRODUCING CERAMIC BODIES | THE DOW CHEMICAL COMPANY (US) | 1990-03-22 | — | — | WO | claimed |
| EP-0358530-A2 | Novel method for producing ceramic bodies | THE DOW CHEMICAL COMPANY (US) | 1990-03-14 | — | — | EP | claimed |
| US-4856294-A | Micro-climate control vest | MAINSTREAM ENGINEERING CORPORATION (US) | 1989-08-15 | — | — | US | claimed |
| US-4824661-A | COPPER SALT, 2,4,4*-TRICHLORO-2*-HYDROXYDIPHENYL ETHER | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1989-04-25 | — | — | US | claimed |
| US-4375425-A | Catalyst for the production of a hydrogen-rich gas | TEXACO INC. (US) | 1983-03-01 | — | — | US | claimed |