Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1578668 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL27901803 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL208379 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL67093 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3229957 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL970907 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28547967 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL19716175 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7804771 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3798286 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590223-B2 | Method for preparing metallopolymer-based coating solution | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2026-03-31 | — | — | US | claimed |
| CN-120622956-B | High-performance ceramic glaze for antibacterial household porcelain and preparation method thereof | 广东大业陶瓷有限公司 | 2026-02-27 | — | — | CN | claimed |
| EP-4630187-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | Bahçesehir Üniversitesi (TR) | 2025-10-15 | — | — | EP | claimed |
| CN-120137373-A | Antistatic automobile window film and preparation method thereof | 浙江时和新材料科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120089743-A | Composite positive electrode lithium supplementing additive and preparation method and application thereof | 合肥国轩高科动力能源有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120026365-A | Copper atom doped cobalt disulfide catalyst and preparation method and application thereof | 电子科技大学 | 2025-05-23 | — | — | CN | claimed |
| CN-119638565-A | Method for preparing benzoic acid by oxidizing toluene at room temperature | 中山大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119504802-A | Copper-cefazolin nano-particles and preparation method and application thereof | 安徽医科大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119456044-A | DMC catalyst for synthesizing methanol by oxidative carbonylation and preparation and application thereof | 太原理工大学 | 2025-02-18 | — | — | CN | claimed |
| EP-4180805-B1 | SCREEN-PRINTED ELECTRODE, MANUFACTURING METHOD THEREOF, ELECTROCHEMICAL SENSOR COMPRISING SAID ELECTRODE FOR DETECTING WATER POLLUTANTS, AND OPERATING METHOD OF SAID SENSOR | CONSEJO SUPERIOR INVESTIGACION (ES) | 2025-01-29 | — | — | EP | claimed |
| US-6476219-B1 | Methods for preparing phthalocyanine compositions | XEROX CORPORATION | 2002-11-05 | — | — | US | claimed |
| US-6221942-B1 | Zircon-carbon for ceramic composite fiber coatings and fine-grained zircon powder | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2001-04-24 | — | — | US | claimed |
| EP-0828558-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1996038226-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0422105-B1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1994-09-07 | — | — | EP | claimed |
| US-5114702-A | Method of making metal oxide ceramic powders by using a combustible amino acid compound | BATTELLE MEMORIAL INSTITUTE (US) | 1992-05-19 | — | — | US | claimed |
| EP-0422105-A4 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | — | 1992-01-08 | — | — | EP | claimed |
| EP-0422105-A1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME. | BATTELLE MEMORIAL INSTITUTE (US) | 1991-04-17 | — | — | EP | claimed |
| WO-1989012027-A1 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1989-12-14 | — | — | WO | claimed |
| US-4550098-A | CATALYTIC OXIDATION | THE BOC GROUP, INC. (US) | 1985-10-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590223-B2 | Method for preparing metallopolymer-based coating solution | TMT1A, TTPA, TMSB10 | MEN1 2533/4885KMT2A 743/4885CA5A 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.