Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1578668 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL27901803 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL208379 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3229957 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL970907 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28547967 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL368324 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL19716175 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7804771 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3798286 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12089591-B2 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY LLC (US) | 2024-09-17 | — | — | US | disclosed |
| US-20230102424-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | MONSANTO TECHNOLOGY LLC | 2023-03-30 | — | — | US | disclosed |
| US-20200407303-A1 | QUINONES AND PROCESS OF OBTAINING SAME | BASF SE (DE) | 2020-12-31 | — | — | US | disclosed |
| EP-3752493-A1 | QUINONES AND PROCESS OF OBTAINING SAME | BASF SE (DE) | 2020-12-23 | — | — | EP | disclosed |
| CN-111712488-A | Quinone compound and method for obtaining same | 巴斯夫欧洲公司 | 2020-09-25 | — | — | CN | disclosed |
| US-20200236930-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | MONSANTO TECHNOLOGY LLC (US) | 2020-07-30 | — | — | US | disclosed |
| WO-2019158514-A1 | QUINONES AND PROCESS OF OBTAINING SAME | BASF SE (DE) | 2019-08-22 | — | — | WO | disclosed |
| EP-1853115-B1 | MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS | MONSANTO TECHNOLOGY LLC (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20170339950-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | MONSANTO TECHNOLOGY LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9642359-B2 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160330956-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | MONSANTO TECHNOLOGY LLC (US) | 2016-11-17 | — | — | US | disclosed |
| US-9364003-B2 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY LLC (US) | 2016-06-14 | — | — | US | disclosed |
| US-20120149569-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | MONSANTO TECHNOLOGY LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-8129564-B2 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY LLC (US) | 2012-03-06 | — | — | US | disclosed |
| CN-101170907-A | Mitigating necrosis in glyphosate tolerant transgenic cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY LLC (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1853115-A2 | MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS | Monsanto Technology, LLC (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070037708-A1 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | MONSANTO TECHNOLOGY, LLC (US) | 2007-02-15 | — | — | US | disclosed |
| WO-2006096617-A2 | MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS | MONSANTO TECHNOLOGY LLC (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407303-A1 | QUINONES AND PROCESS OF OBTAINING SAME | SCO2, SOD1, SQOR | MEN1 654/4885KMT2A 2537/4885CA5A 378/4885 |
| US-20200236930-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-20070037708-A1 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-20170339950-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-20120149569-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-20230102424-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-20160330956-A1 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
| US-12089591-B2 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations | GLO1, AGXT, GRHPR | MEN1 4751/4885KMT2A 2769/4885CA5A 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.