Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709088 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BSIRT2SIRT1CTSK | |
| SCHEMBL11789654 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BSIRT2SIRT1CTSK | |
| SCHEMBL7447157 | 0.87 | FOLH1 (0.51) | ITGB3ITGA2BFOLH1NAALAD2 | |
| SCHEMBL16124669 | 0.83 | NOD1 (0.51) | ITGB3ITGA2BFOLH1NAALAD2 | |
| SCHEMBL10036530 | 0.82 | NOD1 (0.53) | FOLH1NAALAD2 | |
| SCHEMBL16124659 | 0.82 | NOD1 (0.53) | FOLH1NAALAD2 | |
| SCHEMBL11397531 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2BFOLH1ACEACE2 | |
| SCHEMBL751179 | 0.81 | CTSL (0.55) | SIRT2SIRT1FOLH1CTSK | |
| SCHEMBL3630687 | 0.80 | CTSK (0.61) | ITGB3ITGA2BSIRT2SIRT1CTSK | |
| SCHEMBL3659010 | 0.80 | CTSK (0.61) | ITGB3ITGA2BSIRT2SIRT1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |