SCHEMBL2722347

SCHEMBL2722347

CCOC(=O)CCCOCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
LTA4H P09960 6/20 0.51
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
TDP1 Q9NUW8 3/20 0.49
ALDH1A1 P00352 3/20 0.48
POLB P06746 1/20 0.48
CYSLTR2 Q9NS75 1/20 0.47
CYSLTR1 Q9Y271 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TOP2A P11388 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
PPID Q08752 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9212182 0.95 ALOX5 (0.52) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL6105604 0.94 ALOX5 (0.51) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL5400194 0.94 ALOX5 (0.51) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL3630884 0.91 LTA4H (0.49) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL26830309 0.91 LTA4H (0.49) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL10472517 0.90 TDP1 (0.51) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL16672704 0.89 TDP1 (0.51) ALOX5LTA4HTDP1ALDH1A1TOP2A
SCHEMBL6181708 0.89 ALDH1A1 (0.58) TDP1ALDH1A1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL8988940 0.88 ALOX5 (0.49) ALOX5LTA4HCYP4F2CYP4A11TDP1
SCHEMBL3531395 0.88 LTA4H (0.45) ALOX5LTA4HTDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382851-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
EP-2869389-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME MITSUBISHI CHEM CORP (JP) 2019-11-13 EP disclosed
US-10320030-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-11 US disclosed
WO-2018091542-A1 CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF LIVER DISEASES IDENIX PHARMACEUTICALS LLC (US) 2018-05-24 WO disclosed
US-20170158620-A1 COMPOUND WITH BRANCHING ALKYL CHAINS, METHOD FOR PREPARING THE SAME, AND USE THEREOF IN PHOTOELECTRIC DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2017-06-08 US disclosed
US-9611216-B2 Compound with branching alkyl chains, method for preparing the same, and use thereof in photoelectric device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-04-04 US disclosed
US-20150140448-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
EP-2869389-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME Mitsubishi Chemical Corporation (JP) 2015-05-06 EP disclosed
CN-104412441-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2015-03-11 CN disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed
US-8658639-B2 N-substituted-cyclic amino derivative DAINIPPON SUMITOMO PHARMA CO., LTD (JP) 2014-02-25 US disclosed
US-20120122773-A1 N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-05-17 US disclosed
EP-2447264-A1 N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-05-02 EP disclosed
WO-2010135424-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2010-11-25 WO disclosed
US-4874760-A CALCIUM ANTAGONISTS TOA EIYO, LTD. (JP) 1989-10-17 US disclosed
EP-0277701-A1 Thiazolopyridine derivative, their production and cardiovascular treating agents containing them TOA EIYO LTD. (JP) 1988-08-10 EP disclosed
US-4218452-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-08-19 US disclosed
US-4159329-A BLOCKING AGENTS, ANTAGONISTS, ANTIHISTAMINES SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1979-06-26 US disclosed
US-4145546-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158620-A1 COMPOUND WITH BRANCHING ALKYL CHAINS, METHOD FOR PREPARING THE SAME, AND USE THEREOF IN PHOTOELECTRIC DEVICE PCNA, EPCAM, DNMT1 ALOX5 1107/4885LTA4H 752/4885CYP4F2 896/4885
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B ALOX5 88/4885LTA4H 63/4885CYP4F2 1213/4885
US-20230382851-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM HSD17B10, HSD17B12, HSD17B14 ALOX5 287/4885LTA4H 394/4885CYP4F2 493/4885
US-20120122773-A1 N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE REN, AGTR1, AGTR2 ALOX5 4004/4885LTA4H 3192/4885CYP4F2 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.