Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709875 | 0.88 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9709729 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9709687 | 0.73 | CD38 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9709723 | 0.73 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709740 | 0.72 | LTB4R2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9660639 | 0.71 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9709700 | 0.70 | VCP (0.52) | AGTR1AGTR2VCPSCD | |
| SCHEMBL9208929 | 0.69 | PDK2 (0.42) | — | |
| SCHEMBL9709698 | 0.68 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9489948 | 0.67 | ATM (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |