Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488201 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EHTTTLR8 | |
| SCHEMBL8536744 | 0.82 | ARG1 (0.32) | ALDH1A1SMN1; SMN2KDM4EHTTTLR8 | |
| SCHEMBL1681999 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2KDM4EHTTPOLB | |
| SCHEMBL27472573 | 0.75 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2KDM4EHTTARG1 | |
| SCHEMBL1829325 | 0.74 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EHTTTLR8 | |
| SCHEMBL27977503 | 0.73 | PTGS2 (0.43) | ALDH1A1SMN1; SMN2KDM4EPTGS2POLB | |
| SCHEMBL1682004 | 0.72 | CHRNB2 (0.40) | ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL1828858 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTTLR8POLB | |
| SCHEMBL1829860 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHTTTLR8 | |
| SCHEMBL27688678 | 0.68 | TLR8 (0.50) | ALDH1A1TLR8POLBKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089392-A | Medical diagnosis | THE UNITED STATES OF AMERICA AS REPRESENTED BY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-02-18 | — | — | US | disclosed |