Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24527435 | 0.80 | ACHE (0.44) | PTGS2ALDH1A1NOTUMKDM4ETSHR | |
| SCHEMBL8746704 | 0.75 | ADRB1 (0.46) | ALOX5ALDH1A1MAPTGAATSHR | |
| SCHEMBL28226906 | 0.73 | ALDH1A1 (0.77) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL6304342 | 0.73 | TP53 (0.48) | ALOX5PTGS1PTGS2HTR3EHTR3B | |
| SCHEMBL44773 | 0.73 | TP53 (0.48) | ALOX5PTGS1PTGS2HTR3EHTR3B | |
| SCHEMBL4076837 | 0.72 | ALDH1A1 (0.59) | ALOX5PTGS1PTGS2ALDH1A1HTR3E | |
| Bw-755C SCHEMBL2573191 | 0.72 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ALDH1A1HTR3E | |
| Bw-755C SCHEMBL30088397 | 0.72 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ALDH1A1HTR3E | |
| SCHEMBL4069047 | 0.71 | ALDH1A1 (0.68) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| Bw-755C SCHEMBL1040411 | 0.71 | ALOX5 (0.97) | ALOX5PTGS1PTGS2ALDH1A1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019572-A2 | I-AZA-2-PHENYLHYDRORAZINO-HETEROCYCLES, PROCESS FOR PRODUCING THEM AND PHARMACEUTICALS CONTAINING THEM | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |