Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.32 |
| ▸ | VHL | P40337 | 1/20 | 0.32 |
| ▸ | ELOC | Q15369 | 1/20 | 0.32 |
| ▸ | ELOB | Q15370 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713840 | 0.78 | S100A4 (0.44) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL10503278 | 0.72 | S100A4 (0.50) | S100A4HSP90AA1PTPN1PPOXUSP8 | |
| SCHEMBL9627970 | 0.70 | ALDH1A1 (0.57) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL9713740 | 0.70 | BACE1 (0.45) | S100A4HSP90AA1PTPN1PTPN11KDM4E | |
| SCHEMBL8773066 | 0.70 | S100A4 (0.56) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL9713423 | 0.68 | PTPN1 (0.46) | S100A4HSP90AA1PTPN1KDM4E | |
| SCHEMBL9713138 | 0.68 | MAP2K7 (0.44) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL9713379 | 0.68 | S100A4 (0.44) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL23271777 | 0.67 | S100A4 (0.52) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL976245 | 0.67 | HSP90AA1 (0.53) | S100A4HSP90AA1PTPN1PPOXPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |