Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714916 | 0.87 | LMNA (0.41) | TSPO | |
| SCHEMBL9714973 | 0.83 | LMNA (0.42) | — | |
| Hydrochloric Acid SCHEMBL9714930 | 0.82 | LMNA (0.41) | — | |
| SCHEMBL9715039 | 0.80 | LMNA (0.42) | — | |
| SCHEMBL9714924 | 0.79 | HSD17B10 (0.41) | — | |
| Hydrochloric Acid SCHEMBL9714965 | 0.76 | RAB9A (0.53) | — | |
| Hydrochloric Acid SCHEMBL9715064 | 0.73 | PTGDR2 (0.39) | TSPO | |
| SCHEMBL13268006 | 0.64 | KDM4E (0.83) | TSPO | |
| SCHEMBL9539069 | 0.64 | TSPO (0.80) | TSPO | |
| SCHEMBL9738542 | 0.62 | TSPO (0.44) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | claimed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | claimed |
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |