Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9714930 | 0.99 | LMNA (0.41) | LMNAPOLBTYMPDPP4ALPL | |
| SCHEMBL9715021 | 0.88 | PTGDR2 (0.39) | TYMPALPLALDH1A1MAPTKDM4E | |
| SCHEMBL9714916 | 0.88 | LMNA (0.41) | LMNATYMPALPLKDM4E | |
| Hydrochloric Acid SCHEMBL9715064 | 0.86 | PTGDR2 (0.39) | TYMPALPLALDH1A1MAPTKDM4E | |
| SCHEMBL9715039 | 0.85 | LMNA (0.42) | LMNAPOLBDPP4ALPLALDH1A1 | |
| SCHEMBL9714971 | 0.83 | TSPO (0.46) | — | |
| SCHEMBL9714924 | 0.80 | HSD17B10 (0.41) | LMNAALPLALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9714991 | 0.79 | HSD17B10 (0.40) | LMNAALPLALDH1A1KMT2AMEN1 | |
| SCHEMBL9714951 | 0.74 | P2RX7 (0.39) | POLBMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9714965 | 0.74 | RAB9A (0.53) | LMNAPOLBALPLALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |