Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714950 | 0.86 | MAPK1 (0.53) | MAPK1CYP1A2GAAMAP4K4RPS6KA3 | |
| SCHEMBL8514273 | 0.82 | P2RX7 (0.47) | TP53TYMPALPLCA12PTGDR2 | |
| SCHEMBL9715021 | 0.79 | PTGDR2 (0.39) | MAPTCYP1A2CYP2C9CYP2C19TYMP | |
| SCHEMBL20075139 | 0.78 | IKBKB (0.50) | ABL1SRCMAPTMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9715064 | 0.78 | PTGDR2 (0.39) | MAPTCYP1A2CYP2C9CYP2C19TYMP | |
| SCHEMBL9714927 | 0.78 | RAB9A (0.44) | TP53ALPLHTTMAPK10SMN1; SMN2 | |
| SCHEMBL9715031 | 0.73 | PTGDR2 (0.38) | MAPTCYP1A2CYP2C19TP53CYP3A4 | |
| SCHEMBL8025184 | 0.72 | ABL1 (0.54) | ABL1SRCMAPTMAPK1CYP1A2 | |
| SCHEMBL27656187 | 0.71 | ALPL (0.43) | ALPLCA12LMNA | |
| SCHEMBL9714918 | 0.70 | LMNA (0.54) | MAPK1CYP1A2CYP2C9CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |