Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473123 | 0.83 | SMN1; SMN2 (0.57) | POLBEGFRNPC1RAB9AGAA | |
| Oxalic Acid SCHEMBL9536045 | 0.83 | USP2 (0.57) | POLBNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL2744060 | 0.81 | L3MBTL1 (0.62) | L3MBTL1POLBNPC1RAB9AGAA | |
| Bromide SCHEMBL2241396 | 0.79 | L3MBTL1 (0.60) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL9536253 | 0.79 | FDPS (0.45) | NPC1RAB9AGAAALDH1A1ALOX15 | |
| SCHEMBL9537775 | 0.75 | NPC1 (0.52) | L3MBTL1NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL1810549 | 0.74 | L3MBTL1 (0.57) | L3MBTL1POLBNPC1RAB9AGAA | |
| SCHEMBL28305604 | 0.71 | L3MBTL1 (0.47) | L3MBTL1POLBDHFREGFRGAA | |
| SCHEMBL9715442 | 0.70 | DHFR (0.50) | L3MBTL1POLBDHFREGFRNPC1 | |
| SCHEMBL1809197 | 0.69 | L3MBTL1 (0.68) | L3MBTL1POLBNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343893-B1 | AROMATIC AND HETEROCYCLIC CARBOXAMIDE DERIVATIVES AS ANTINEOPLASTIC AGENTS | PFIZER INC. (US) | 1992-08-05 | — | — | EP | disclosed |