SCHEMBL9720733

SCHEMBL9720733

Cc1ccc(-c2nc(CNC3CCCCC3)c(C)[nH]2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 2/20 0.50
HRH3 Q9Y5N1 1/20 0.44
KDM4E B2RXH2 2/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
CTSS P25774 1/20 0.39
OPRL1 P41146 3/20 0.39
KCNH2 Q12809 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
LMNA P02545 1/20 0.37
CNR1 P21554 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720797 0.99 GRIN2B (0.51) GRIN2BHRH3KDM4EPKMKMT2A
SCHEMBL9720802 0.77 SMN1; SMN2 (0.41) GRIN2BKDM4EPKMKMT2AMEN1
SCHEMBL9720685 0.73 KDM4E (0.39) GRIN2BKDM4EKMT2AMEN1ALDH1A1
SCHEMBL9720698 0.72 GRIN2B (0.41) GRIN2BMAPTCTSSRAB9A
SCHEMBL8807968 0.72 HRH3 (0.83) HRH3KDM4EKMT2AMEN1HPGD
SCHEMBL9720794 0.72 LMNA (0.40) GRIN2BKDM4EALDH1A1CTSSRAB9A
SCHEMBL9720668 0.71 DRD2 (0.55) GRIN2BKDM4EALDH1A1CTSSNPC1
SCHEMBL6649887 0.70 TNKS (0.41) KDM4EKMT2AMEN1ALDH1A1HPGD
SCHEMBL19350091 0.70 CTSS (0.41) MAPTCTSSRAB9A
SCHEMBL9720872 0.70 VSIR (0.45) KDM4EKMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142052-A Cationic effect-driven carbinol/amine reaction LABORATOIRES SYNTEX (FR) 1992-08-25 US disclosed