Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723061 | 0.87 | GABRA2 (0.37) | HCAR1GABRB3DDR1 | |
| SCHEMBL9723134 | 0.83 | POLB (0.40) | POLB | |
| SCHEMBL9340204 | 0.82 | HCAR1 (0.30) | HCAR1 | |
| SCHEMBL9339495 | 0.81 | GABRA2 (0.40) | GABRB3DDR1 | |
| SCHEMBL9723095 | 0.77 | HCAR1 (0.36) | HCAR1GABRB3POLB | |
| SCHEMBL9340328 | 0.77 | ALDH1A1 (0.43) | POLB | |
| SCHEMBL9683955 | 0.73 | GAA (0.38) | GABRB3DDR1 | |
| SCHEMBL9723082 | 0.73 | GABRP (0.33) | GABRB3 | |
| SCHEMBL9340200 | 0.72 | TDP1 (0.44) | GABRB3POLB | |
| SCHEMBL9339513 | 0.70 | ALDH1A1 (0.47) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |